Detalhe da pesquisa
1.
High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models.
Cell
; 183(2): 429-441.e16, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32941803
2.
Animal models for COVID-19.
Nature
; 586(7830): 509-515, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32967005
3.
Generation of a humanized mAce2 and a conditional hACE2 mouse models permissive to SARS-COV-2 infection.
Mamm Genome
; 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38488938
4.
Bepridil is potent against SARS-CoV-2 in vitro.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33597253
5.
Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection.
PLoS Pathog
; 17(9): e1009897, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34492082
6.
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection.
Proc Natl Acad Sci U S A
; 117(47): 29832-29838, 2020 11 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33139569
7.
Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease.
J Infect Dis
; 219(5): 829-835, 2019 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30256968
8.
A Highly Immunogenic, Protective, and Safe Adenovirus-Based Vaccine Expressing Middle East Respiratory Syndrome Coronavirus S1-CD40L Fusion Protein in a Transgenic Human Dipeptidyl Peptidase 4 Mouse Model.
J Infect Dis
; 220(10): 1558-1567, 2019 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30911758
9.
Viromimetic STING Agonist-Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus.
Adv Funct Mater
; 29(28): 1807616, 2019 Jul 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32313544
10.
Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease.
J Virol
; 90(1): 57-67, 2016 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26446606
11.
Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology.
J Virol
; 89(6): 2995-3007, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25520500
12.
Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin.
J Virol
; 89(21): 10970-81, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26311885
13.
Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease.
J Virol
; 89(7): 3659-70, 2015 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-25589660
14.
Inducible Epithelial Resistance against Coronavirus Pneumonia in Mice.
Am J Respir Cell Mol Biol
; 63(4): 540-541, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32706609
15.
Blocking of exchange proteins directly activated by cAMP leads to reduced replication of Middle East respiratory syndrome coronavirus.
J Virol
; 88(7): 3902-10, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24453361
16.
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.
J Virol
; 88(12): 7045-53, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24719424
17.
Bilateral entry and release of Middle East respiratory syndrome coronavirus induces profound apoptosis of human bronchial epithelial cells.
J Virol
; 87(17): 9953-8, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23824802
18.
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.
J Virol
; 87(7): 3885-902, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23365422
19.
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations.
Sci Transl Med
; 16(738): eadi0979, 2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38478629
20.
Human metapneumovirus M2-2 protein inhibits innate cellular signaling by targeting MAVS.
J Virol
; 86(23): 13049-61, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23015697